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yesbiotech/mAb anti-Human IFN-γ, 23/0.1 mg/MO-C40004F

yesbiotech/mAb anti-Human IFN-γ, 23/0.1 mg/MO-C40004F
  • yesbiotech/mAb anti-Human IFN-γ, 23/0.1 mg/MO-C40004F
商品介绍
  • Description
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Description

Details

Description:Mouse monoclonal antibody to human Interferon-gamma (IFN-γ)

Purification: Protein G affinity purified

Target Protein: HumanIFN-γ

Immunogen: Purified recombinant humanIFN-γ

Fusion Myeloma: Sp2/0-Ag14

Specificity:This antibody recognizes both recombinant and native human IFN-γ.

Species Reactivity: Human, other species not tested

Host / Isotype: Mouse, IgG1 Kappa

Formulation: Lyophilized from a solution in 0.01M PBS, pH 7.0

Reconstitution: Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20oC

Research Area:Pro-inflammatory cytokine, anti-tumour and anti-viral immunity

Background:

IFN-γ is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL), effector T cells once antigen-specific immunity develops. IFN-γ stimulates its own expression and up-regulates other genes to stimulate and modulate immunity mainly through the Jak-Stat signalling pathway. It promoters T helper 1 differentiation and cell associated immunity, and also suppresses T helper 2 differentiation and humoral immunity.

IFN-γ is a potent macrophage activator. It binds to macrophage in conjugation with CD40, causing the macrophage to produce elevated amounts ofMHCmolecules. It also stimulates the production of antigen-processing associated transporters and enzymes.

IFN-γ is critical for anti-tumour and anti-viral immunity.

Applications:

ELISA:The antibody reacts with recombinant IFN-γ coated plate at 0.1ng/mL of antibody concentration.

References: If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.

Additional

Additional Information

Product SpecificitymAb anti-Human IFN-γ, 23
ApplicationEIA
Size0.1 mg
品牌介绍

Anogen-Yes Biotech Laboratories Ltd.是一家位于加拿大密西沙加的生物技术公司。成立于1989年,我们30年来一直是高质量抗体基产品的骄傲供应商。我们提供300多种单克隆和多克隆抗体,以及60多种类型的ELISA试剂盒,用于研究,诊断和治疗应用。


作为一家专注于研究的公司,我们还开发了许多专有的诊断和治疗产品。我们的产品Abcream是一种有效的抗牛皮癣局部抗IL-8(CXCL8)单克隆抗体,已于2001年获得中国国家食品药品监督管理局(SFDA)的批准,并获得多项国际专利。我们的用于诊断目的的新生儿TSH ELISA试剂盒也已获得加拿大卫生部的许可。我们还启动了针对炎症,阿尔茨海默氏病和癌症的研究和开发产品。


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