Description:Mouse monoclonal antibody (mAb) to human cluster of differentiation 11 alpha chain (CD11α) or mAb to human lymphocyte function associated factor I (LFA-1) alpha chain.
Purification:Protein G affinity purified
Product Type:Primary antibody
Target Protein:Human CD11α
Immunogen:Human cytolytic T lymphocytes
Fusion Myeloma:Sp2/0-Ag14
Specificity:This antibody is reactive to human CD11α.
Species Reactivity:Human, others not tested.
Host / Isotype:Mouse, IgG1 Kappa
Formulation:Lyophilized from a solution in 0.01M PBS, pH 7.0
Reconstitution:Double distillated water is recommended to adjust the final concentration to 1.00mg/mL.
Storage: Store at -20oC
Research Area:Immunology
Background:
CD11α comprises the alpha-chain of lymphocyte function associated factor I (LFA-1). LFA-1 is an adhesion molecule expressed on the surface of T cell, B cell, macrophage, monocytes and neutrophils. LFA-1 plays a role in lymphocyte recruitment to site of infection. LFA-1 initiates a weak link between lymphocytes and antigen presentation cells (APC) by binding to intercellular adhesion molecule 1 (ICAM-1) on APC.
Application:
Fluorescence flow cytometry:Above (see image) is the histogram of Jurkat cells stained with 10mg/ml mouse anti-human CD11α monoclonal antibody. Black line histogram represents Jurkat cells stained with isotype control, mouse anti-TB 38Kd antigen monoclonal antibody (MO-I40021D, B12F8).
Immuno-histochemistry
References:
If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.
Product Specificity | mAb anti-Human CD11α, A11 |
---|---|
Application | IF, IHC |
Size | 0.1 mg |
Anogen-Yes Biotech Laboratories Ltd.是一家位于加拿大密西沙加的生物技术公司。成立于1989年,我们30年来一直是高质量抗体基产品的骄傲供应商。我们提供300多种单克隆和多克隆抗体,以及60多种类型的ELISA试剂盒,用于研究,诊断和治疗应用。
作为一家专注于研究的公司,我们还开发了许多专有的诊断和治疗产品。我们的产品Abcream是一种有效的抗牛皮癣局部抗IL-8(CXCL8)单克隆抗体,已于2001年获得中国国家食品药品监督管理局(SFDA)的批准,并获得多项国际专利。我们的用于诊断目的的新生儿TSH ELISA试剂盒也已获得加拿大卫生部的许可。我们还启动了针对炎症,阿尔茨海默氏病和癌症的研究和开发产品。