Description:Rabbit anti-Mouse transient receptor potential cation channel V3 (TRPV3) polyclonal antibody

Purification: Protein G affinity purified

Product Type:Primary antibody

Target Protein:Transient receptor potential cation channel V3 (TRPV3)

Immunogen:A synthetic peptide (YRPREEEAI) corresponding to amino acid 461-469 of mouse TRPV3, conjugated with KLH for immunization

Specificity:This antibody is reactive to the 91kDa TRPV3 from mouse brain tissue on Western blot.

Species Reacitvity:Mouse and other species with consensus TRPV3 sequence (YRPREEEAI)

Source:Rabbit

Formulation:Lyophilized in pH 7.4, 0.01M PBS

Reconstitution:Double distilled water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage:Store at -20^oC

Research Area:Life science research, stem cell factor signalling, cancer research

Background:

Mouse transient receptor potential cation channel V3 (TRPV3) belongs to the family of transient receptor potential ion channels. The members of the family have similar tetramer structure and have shown polymodal activation. TRPV3 is a warmth sensor. It is activated at temperatures between 22 and 40 ^oC. TRPV3 is thought to be able to form hybrid channel with TRPV1 through hetero-assemble of the monomers. In human, the genes for TRPV3 and TRPV1 are located on chromosome 17.

Application:

ELISA:Dilute the antibody approx. 1:5,000 for detection of TRPV3 peptide (YRPREEEAI) coated on ELISA plate.

Western blot:Dilute approx. 1:2,000 for using in Western blotting to detect the 91kDa TRPV3 in mouse brain tissue extract.

Fig.1 Western blot analysis of extracts from mouse brain using anti-TRPV3 rabbit whole antiserum.

References:

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