Description:Mouse monoclonal antibody to human chorionic gonadotropin (hCG)

Purification:Protein G affinity purified

Product Type:Primary antibody- capture antibody in matched antibody pair

Target Protein:Human chorionic gonadotropin

Immunogen:Purified human chorionic gonadotropin from urine

Fusion Myeloma:Sp2/0-Ag14

Specificity:Reactive to chorionic gonadotropin alpha subunit (hCG-α)

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG1 Kappa

Formulation:Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution:Double distillated water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20^oC

Research Area:Hormone, pregnancy

Background:

Human chorionic gonadotropin (hCG) is a glycoprotein hormone produced by placenta after conception. hCG is comprised of anαsubunit with 92 amino acids and aβsubunit with 245 amino acids. The a subunit is identical to that of LH (Luteinizing hormone), FSH (Follicle stimulating hormone) and TSH (Thyroid stimulating hormone). hCG sustains corpus luteum, stimulates progesterone secretion, hence is critical to early fetal development. It has also been reported that hCG plays a role in the development of fetal tolerance to maternal immunity. hCG is the most sensitive biomarker for pregnancy.

Application:

ELISA: In combination with HRP conjugated anti-HCG βsubunit antibody (Cat No: MO-M40049T), this antibody can be used as capturer in Sandwich ELISA for quantitative determination of HCG.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.