Description:Mouse monoclonal antibody to human prolactin (PRL)

Purification:Protein G affinity purified

Product Type:Primary antibody- capture antibody in matched antibody pair

Target Protein:Human PRL

Immunogen:Human 23kDa prolactin

Fusion Myeloma:Not known

Reactivity:Human PRL

Species Reacitvity: Human, others not tested

Host / Isotype: Mouse, IgG1 Kappa

Formulation:Lyophilized from a solution in 0.01M PBS, pH 7.2

Reconstitution:Double distillated water is recommended to adjust the final concentration to 1.00 mg/mL.

Storage: Store at -20^oC

Research Area:Hormone, lactation

Background:

Prolactin (PRL) is primarily secreted by pituitary gland. The hormone stimulates mammary gland development during pregnancy and the lactation period after childbirth. PRL has several variations with molecular weights ranging from 22kDa to 150kDa. PRL receptors are mainly located at mammary glands, but also found in other organs and tissues. PRL can bind to cytokine-like receptors and influence haematopoiesis, angiogenesis, and immune response. Anterior pituitary tumours can cause persistent elevation of PRL with clinical signs such as abnormal lactation, infertility and lack of menstrual flow in women, and incompetence in men.

Application:

ELISA:In combination with our matched anti-PRL tracer antibody [anti- human PRL antibody, HRP-conjugated, Cat No: MO-M40047T], this antibody can be used as capture antibody in sandwich ELISA for human PRL detection. The suggested coating concentration is 4μg/mL.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.