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主营:分子类,蛋白类,抗体类,生化类试剂
℡ 4000-520-616
℡ 4000-520-616
yesbiotech/mAb anti-Amyloid β Peptide 42, CA9 10C11, Tracer (Biotin)/0.1 mL/MO-M40093TB
产品编号:MO-M40093TB
市  场 价:¥6300.00
场      地:美国(厂家直采)
联系QQ:1570468124
电话号码:4000-520-616
邮      箱: info@ebiomall.com
美  元  价:$315.00
品      牌: yesbiotech
公      司:yesbiotech
公司分类:
yesbiotech/mAb anti-Amyloid β Peptide 42, CA9 10C11, Tracer (Biotin)/0.1 mL/MO-M40093TB
商品介绍
  • Description
  • Additional

Description

Details

Description:Biotin conjugated mouse monoclonal antibody to C-terminal of amyloid beta peptide 42 (Aβ42)

Purification:Protein G affinity purified

Product Type:Tracer antibody in matched antibody pair, biotin conjugated

Target Protein:C-terminal of amyloid beta peptide 42

Immunogen:KLH conjugated to a short peptide (MVGGVVIA) with amino acid sequence corresponding to the C-terminal of Aβ42

Fusion Myeloma:Sp2/0-Ag14

Specificity:This antibody recognizes the C-terminal sequence (MVGGVVIA) of Aβ42 and full length Aβ42.

Cross-Reactivity:The antibody does not cross react with amyloid beta peptide 40 in dot blotting and ELISA. Cross-reactivity to amyloid beta peptide 43 is less than 1% in ELISA.

Species Reacitvity:Human and other primates; mouse, rat

Host / Isotype: Mouse, IgG2b Kappa

Storage BufferFormulation:0.01M PBS, pH 7.0 ± 0.1 in 1% gelatin and 0.1% proclin-300

Storage: Store at -20oC. Avoid repeated freeze and thaw cycles.

Research Area:Aging and neurodegenerative diseases

Background:

Amyloid beta peptide 42 (Aβ42) is best known for its role in the formation of senile plaques in the brain of patients with Alzheimer’s disease. Aβ42 and Aβ40 are the two major amyloid peptides that are produced after cleavage of amyloid precursor protein by secretases. Aβ42 (42 amino acids) is very fibrillogenic. The beta pleated structure of Aβ42 constituents the initial and key component of the insoluble amyloid fibril in senile plaque. It is widely accepted that Aβ42 contributes to the pathogenesis of Alzheimer’s disease. One proposition is that the deposition of amyloid fibril onto the brain tissue results in Alzheimer’s disease. Another is that the neurotoxicity of Aβ42 oligomer is the cause of the disease.

Application:

ELISA:In combination with capturer anti-amyloid peptide N-terminal antibody (mAb clone NT 5B8, Cat. No.: MO-M40094D) and avidin-HRP conjugate, this biotin conjugated antibody can detect Aβ42 in Sandwich ELISA assay.

References:

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.

Additional

Additional Information

Product SpecificitymAb anti-Amyloid β Peptide 42, CA9 10C11, Tracer (Biotin)
ApplicationEIA
Size0.1 mL
品牌介绍

Anogen-Yes Biotech Laboratories Ltd.是一家位于加拿大密西沙加的生物技术公司。成立于1989年,我们30年来一直是高质量抗体基产品的骄傲供应商。我们提供300多种单克隆和多克隆抗体,以及60多种类型的ELISA试剂盒,用于研究,诊断和治疗应用。


作为一家专注于研究的公司,我们还开发了许多专有的诊断和治疗产品。我们的产品Abcream是一种有效的抗牛皮癣局部抗IL-8(CXCL8)单克隆抗体,已于2001年获得中国国家食品药品监督管理局(SFDA)的批准,并获得多项国际专利。我们的用于诊断目的的新生儿TSH ELISA试剂盒也已获得加拿大卫生部的许可。我们还启动了针对炎症,阿尔茨海默氏病和癌症的研究和开发产品。


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