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yesbiotech/mAb anti-Amyloid β Peptide N-terminal, NT 6C8/0.5 mg/MO-M40094C

yesbiotech/mAb anti-Amyloid β Peptide N-terminal, NT 6C8/0.5 mg/MO-M40094C
  • yesbiotech/mAb anti-Amyloid β Peptide N-terminal, NT 6C8/0.5 mg/MO-M40094C
商品介绍
  • Description
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Description

Details

Description:Mouse monoclonal antibody against N-terminal sequence of human amyloid beta peptides

Purification:Protein G affinity purified

Target Protein:N-terminal sequence of human beta amyloid peptide

Immunogen:N-terminal peptide (DAEFRHDS) of human beta amyloid peptides, conjugated with KLH

Fusion Myeloma:Sp2/0-Ag14

Specificity:This antibody recognizes the N-terminal peptide (DAEFRHDS) of human beta amyloid peptides and also reacts with full length Aβ40, Aβ42 and Aβ43.

Species Reacitvity:Human

Host / Isotype: Mouse, IgG1 Kappa

Formulation:Lyophilized from a solution in 0.01M PBS pH7.2

Reconstitution:Double distilled water is recommended to adjust the final concentration to 1.00mg/mL.

Storage: Store at -20oC

Research Area:Aging and neurodegenerative diseases

Background:

Amyloid beta peptides Aβ42 and Aβ40 have been investigated extensively for predicating Alzheimer’s disease. A recent study on amyloid beta peptide Aβ43 in brain showed that Aβ43 is more fibrillogenic than other amyloid beta peptides and could be more useful as a biomarker or therapeutic target for Alzheimer’s disease.

Since Aβ40, Aβ42 and Aβ43 are different only at the few C-end amino acids, antibody to N-terminal sequence can bind with all three amyloid beta peptides.

Application:Immunohistochemistry,ELISA

References:

Y Zhang et al., Amyloid-β induces hepatic insulin resistance in vivo via JAK2. Diabetes (2013) 62, 4:1159-1166

If research is published using this product, please inform Anogen in order to cite the reference on this datasheet. Anogen will provide one unit of product in the same category as gratitude.

Additional

Additional Information

Product SpecificitymAb anti-Amyloid β Peptide N-terminal, NT 6C8
ApplicationIHC, EIA
Size0.5 mg
品牌介绍

Anogen-Yes Biotech Laboratories Ltd.是一家位于加拿大密西沙加的生物技术公司。成立于1989年,我们30年来一直是高质量抗体基产品的骄傲供应商。我们提供300多种单克隆和多克隆抗体,以及60多种类型的ELISA试剂盒,用于研究,诊断和治疗应用。


作为一家专注于研究的公司,我们还开发了许多专有的诊断和治疗产品。我们的产品Abcream是一种有效的抗牛皮癣局部抗IL-8(CXCL8)单克隆抗体,已于2001年获得中国国家食品药品监督管理局(SFDA)的批准,并获得多项国际专利。我们的用于诊断目的的新生儿TSH ELISA试剂盒也已获得加拿大卫生部的许可。我们还启动了针对炎症,阿尔茨海默氏病和癌症的研究和开发产品。


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